A novel approach for studying histone H1 function in vivo.

نویسندگان

  • Giorgia Siriaco
  • Renate Deuring
  • Gina D Mawla
  • John W Tamkun
چکیده

In this report, we investigate the mechanisms that regulate Drosophila histone H1 expression and its association with chromatin in vivo. We show that histone H1 is subject to negative autoregulation and exploit this result to examine the effects of mutations of the main phosphorylation site of histone H1.

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عنوان ژورنال:
  • Genetics

دوره 200 1  شماره 

صفحات  -

تاریخ انتشار 2015